Center for Integration of Science and Industry

Mission

The mission of the Center for Integration of Science and Industry is to "understand the process by which science is translated for public value, and accelerate this translation by engaging science and industry in interdisciplinary dialogue, scholarship, and education."

The Center brings together the perspectives of natural science, business, analytics, and policy to understand, and advance, the path of translational science and the business models that create public value from the fruits of scientific discovery.

Our Center exemplifies Bentley’s commitment to 'good business' by engaging in scholarship designed to advance pharmaceutical innovation as well as the availability and affordability of life-saving drugs. We’re honored our work has had a significant impact on business practice and public policy.

Dr. Fred Ledley

Director, Center for Integration of Science and Industry

Research & News

Impact of IRA price negotiations on new drug pipeline

Our recent study shows that existing strategic management practices in pharma could mitigate any negative impacts of the Inflation Reduction Act on profit or productivity.

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Implications of the IRA for the biotechnology industry

Our recent study shows that investment in pharmaceutical innovation is unlikely to be affected by the Inflation Reduction Act and will continue to provide the capital necessary for early-stage innovation and development in biotechnology companies.

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Association between expedited review designations and the US or global burden of disease

Our recent study shows that expedited approval programs may disincentivize development of drugs for conditions associated with the greatest burden of disease.

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Considering returns on federal investment in negotiated “maximum fair price” of drugs under IRA

Our recent study shows that the NIH spent $11.7 billion on research leading to approval of drugs selected for price negotiations in year one of the Inflation Reduction Act.

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Research spending on new drug approvals by NIH vs industry

Our recent study shows NIH investment in new drug approvals is comparable to investment by the pharmaceutical industry.

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Dr. Lawrence Tabak references our work in his testimony

Dr. Lawrence Tabak, Director of the NIH states, "An independent analysis by researchers at Bentley University found that NIH funding contributed to development of every new drug, all 356, approved by the FDA from 2010-2019." (43:46)

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Research Highlights

The White House References Our Work

On December 7, 2023, the Biden-Harris Administration announced new actions to lower health care and prescription drug costs while citing our working paper.

Read the Statement

Congressional Testimony

At a September 25, 2019 hearing of the House Appropriations Subcommittee on Labor, Health and Human Services, Education, and Related Agencies, Representative Mark Pocan asked Dr. Francis Collins, Director of the NIH, if the Center for Integration of Science and Industry was planning to expand on the 2018 study, published in PNAS, establishing that NIH funding contributed to every new drug approved by the FDA from 2010-2016. Researchers at the Center extended this analysis through 2019 in a 2020 working paper published by INET.

Watch Full Testimony

Alexandria Ocasio-Cortez Stands Up to Big Pharma

Representative Alexandria Ocasio-Cortez uses information from the Center for Integration of Science and Industry's PNAS paper.

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Interactive Dashboards

Impact of Drug Price on Pipeline of New Drug Launches

Enables you to model the impact of drug price reductions of 0-20% with differential allocation of cost reductions through phased clinical development.

NIH Funding Drug Innovation

Enables public use of the python-powered search method described from "Spending on Phased Clinical Development of Approved Drugs by the US National Institutes of Health Compared With Industry."

Student Alumni Spotlight

Sarah Al-Masri '22

"I remember applying to the Center of Integration of Science and Industry during the winter break of my Junior year (December 2020). It was during the height of the pandemic when I was doing all of my classes online. During that time, I realized I wanted to pursue a career in research and academia, so I was excited to see a listing for a Research Assistantship at CISI. The year I spent working at the Center was an incredibly memorable year and one that gave me so much experience to be able to continue doing research in this field. ..."

Contact Us

Location: Jennison 143 | Telephone: (781) 891-2984 | Email: GA_SciIndustry@bentley.edu